Appendix 1—table 1. Summary of the UKBB cohort individuals.
The UKBB cohort was split into six disjoint, self-reported ancestries. For each ancestry, we summarized the background information for the phenotype (number of UL cases and female controls), proportion of cases (%), age at first assessment visit (mean and SD), number of live births (mean and SD), body mass index (BMI; mean and SD), proportion of hysterectomy cases (%) and age at hysterectomy (mean and SD).
| Age at first assessment visit | Number of live births | BMI | Age at hysterectomy | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Self-reported ancestry | Phenotype | N | Cases (%) | Mean | SD | Mean | SD | Mean | SD | Ever had hyst. (%) | Mean | SD |
| White British | cases | 15453 | 7.0 | 56.9 | 7.5 | 1.7 | 1.2 | 27.7 | 5.2 | 31.9 | 46.1 | 9.0 |
| controls | 205157 | 56.7 | 7.9 | 1.8 | 1.2 | 27.0 | 5.1 | 7.0 | 42.2 | 10.3 | ||
| Black African | cases | 296 | 19.1 | 49.6 | 6.8 | 2.0 | 1.7 | 31.2 | 5.6 | 22.1 | 45.1 | 8.8 |
| controls | 1256 | 51.8 | 8.1 | 2.8 | 1.8 | 31.3 | 5.7 | 6.5 | 36.4 | 15.4 | ||
| Black | cases | 668 | 24.7 | 50.6 | 6.8 | 1.5 | 1.4 | 30.0 | 6.3 | 24.0 | 41.2 | 12.1 |
| Caribbean | controls | 2041 | 53.0 | 8.2 | 2.2 | 1.7 | 29.8 | 5.9 | 9.7 | 37.2 | 14.8 | |
| White Irish |
cases | 398 | 6.0 | 56.5 | 7.6 | 1.8 | 1.4 | 27.8 | 5.2 | 32.6 | 46.6 | 7.2 |
| controls | 6208 | 56.4 | 8.1 | 1.9 | 1.4 | 26.9 | 5.0 | 7.5 | 42.9 | 10.8 | ||
| Asian Indian | cases | 203 | 7.3 | 53.8 | 7.9 | 2.0 | 1.1 | 27.6 | 4.2 | 33.5 | 44.1 | 11.9 |
| controls | 2567 | 53.7 | 8.0 | 2.0 | 1.2 | 27.1 | 4.8 | 6.6 | 39.8 | 13.9 | ||
| Other white | cases | 647 | 6.7 | 54.8 | 7.9 | 1.3 | 1.2 | 26.7 | 5.3 | 23.6 | 46.5 | 8.6 |
| background | controls | 8982 | 54.6 | 8.3 | 1.6 | 1.2 | 26.4 | 5.2 | 5.4 | 42.1 | 11.0 | |