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. Author manuscript; available in PMC: 2019 Jan 1.
Published in final edited form as: Adv Protein Chem Struct Biol. 2017 Oct 6;111:1–59. doi: 10.1016/bs.apcsb.2017.08.003

Fig. 15.

Fig. 15

The structure of the designed template compound 5 and a peptidomimetic (B) along with the PPI site (A) of the EGFR homodimer of domain IV (PDB ID 1N8Z and 3NJP). Note that the PPI site is dominated by hydrophobic residues. Peptidomimetic can bind to this PPI site. PyMol (Schrodinger LLC, OR) was used to generate the structure of the protein complexes.