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. Author manuscript; available in PMC: 2019 Jan 1.
Published in final edited form as: Adv Protein Chem Struct Biol. 2017 Oct 6;111:1–59. doi: 10.1016/bs.apcsb.2017.08.003

Fig. 16.

Fig. 16

Structures of the B7/CD28 family. Structures are modeled on the crystal determinations. Loops have been added to one end of the IgV domains to emphasize the orientation of the CDR-like loops and their interaction with ligand or lack thereof. Reproduced with permission from Freeman, G. J. (2008). Structures of PD-1 with its ligands: Sideways and dancing cheek to cheek. Proceedings of the National Academy of Sciences of the United States of America, 105(30), 10275–10276. https://doi.org/10.1073/pnas.0805459105. Copyright (2008) National Academy of Sciences, USA.