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. Author manuscript; available in PMC: 2019 Nov 1.
Published in final edited form as: Arthritis Rheumatol. 2018 Sep 24;70(11):1732–1744. doi: 10.1002/art.40578

Figure 5.

Figure 5

ACPA B cells and RF B cells exhibit distinct transcriptional programs that promote antibody class-switching and B-cell activation. (A) Subset-stratified plot of average partial residual expression in the antibody response module (15 genes). * = P<0.05 (B) Subset-stratified plot of average partial residual expression in the B-cell activation module (25 genes). * = P<0.05 (C) Z-scores testing for differential expression between ACPA and RF B cells in antibody response genes. (D) Z-scores testing for differential expression between ACPA and RF B cells in B-cell activation genes.

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