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. Author manuscript; available in PMC: 2019 Nov 1.
Published in final edited form as: Arthritis Rheumatol. 2018 Sep 24;70(11):1835–1846. doi: 10.1002/art.40566

Figure 2.

Figure 2

Total IgG and IgG subclasses of B. burgdorferi antibodies and 3 Lyme disease (LD)-associated autoantibodies in serum and synovial fluid (SF) of patients with antibiotic-responsive or antibiotic-refractory Lyme arthritis. The numbers of patients in each group were as follows: responsive arthritis in serum (N= 55) and SF (N= 17), and in refractory arthritis in serum (N=82) and SF (N= 31). For each assay, the antibody responses to B. burgdorferi (A) or Lyme disease autoantigens (B) were determined by ELISA. The shaded grey areas correspond to 3 SD above the mean value of healthy control subjects. The antibody values between groups were compared using an unpaired t-test with Welch’s correction. Only significant differences are shown. Matrix metalloproteinase-10 = MMP-10, endothelial cell growth factor = ECGF, apolipoprotein B-100 = apoB-100.