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IgG1 and IgG4 B. burgdorferi antibodies and 3 Lyme disease autoantibodies in synovial fluid from 31 patients with antibiotic-refractory Lyme arthritis (LA). The values in the same patient are connected by lines. The differences between IgG1 and IgG4 antibody absorbance values were determined by paired t-test with Welch’s correction. Only significant differences are shown. Matrix metalloproteinase-10 = MMP-10, endothelial cell growth factor = ECGF, apolipoprotein B-100 = apoB-100.
