Fimasartan attenuated ICH-induced NLRP3 inflammasome activation. Twenty-four hours after ICH, the density of NLRP3 (B), ASC (C), caspase-1 (D) and IL-1β (E) in the control group was higher than in the sham group. After administration of low-dose fimasartan, the density of these inflammasome components in the fimasartan group was significantly lower than in the control group. Data are presented as the mean ± SEM from three independent experiments. n = 4 per group; * p < .05, ** p < .01, *** p < .001.