Table 1.
Predictors of Severe RV Failure
| Overall (N=216) | No Severe RVF (N=142) | Severe RVF (N=74) | p-value | |
|---|---|---|---|---|
| Age | 58.12 ± 10.94 | 57.14 ± 11.42 | 59.99 ± 9.78 | 0.07 |
| Male | 173 (80%) | 109 (77%) | 64 (86%) | 0.11 |
| White | 166 (77%) | 106 (75%) | 60 (81%) | 0.14 |
| BMI | 28.69 ± 5.70 | 28.20 ± 5.68 | 29.63 ± 5.66 | 0.08 |
| ICM | 98 (45%) | 61 (43%) | 37 (50%) | 0.39 |
| Diabetes | 96 (44%) | 61 (43%) | 35 (47%) | 0.57 |
| Redo Sternotomy | 59 (27%) | 34 (24%) | 25 (34%) | 0.15 |
| COPD | 33 (15%) | 21 (15%) | 12 (16%) | 0.84 |
| Bridge to Transplant | 137 (63%) | 94 (66%) | 43 (58%) | 0.21 |
| HeartMate II | 179 (83%) | 119 (84%) | 60 (81%) | 0.70 |
| Intermacs Profile | 2.0 (2.0, 2.0) | 2.0 (2.0, 2.0) | 2.0 (1.0, 2.0) | 0.49 |
| Creatinine | 1.4 (1.0, 2.0) | 1.3 (1.0, 1.8) | 1.6 (1.2, 2.1) | 0.04 |
| INR | 1.4 (1.3, 1.6) | 1.4 (1.2, 1.5) | 1.5 (1.3, 1.7) | 0.02 |
| Albumin | 3.62 ± 0.49 | 3.69 ± 0.48 | 3.50 ± 0.51 | 0.008 |
| Intubated pre-LVAD | 11 (5%) | 5 (4%) | 6 (8%) | 0.19 |
| Total bilirubin | 1.0 (0.6, 1.7) | 1.0 (0.6, 1.5) | 1.3 (0.8, 2.2) | 0.002 |
| RA pressure (RHC) | 15.86 ± 6.84 | 14.58 ± 6.52 | 18.30 ± 6.81 | <0.001 |
| Systolic PAP | 58.55 ± 13.82 | 58.06 ± 13.33 | 59.47 ± 14.77 | 0.48 |
| Diastolic PAP | 31.11 ± 7.48 | 30.35 ± 7.19 | 32.57 ± 7.87 | 0.04 |
| Mean PAP | 40.25 ± 8.98 | 39.60 ± 8.61 | 41.50 ± 9.57 | 0.14 |
| PCWP | 27.78 ± 7.79 | 27.09 ± 7.61 | 29.14 ± 8.01 | 0.07 |
| Cardiac Index (Fick) | 1.80 ± 0.50 | 1.78 ± 0.50 | 1.85 ± 0.51 | 0.29 |
| Ejection fraction | 17.99 ± 6.65 | 18.11 ± 6.35 | 17.77 ± 7.25 | 0.73 |
| RA pressure (echo) | 13.47 ± 5.13 | 12.73 ± 5.17 | 14.96 ± 4.73 | 0.003 |
| TR Peak Velocity | 2.92 ± 0.54 | 2.98 ± 0.55 | 2.81 ± 0.52 | 0.04 |
| TAPSE | 1.47 ± 0.46 | 1.55 ± 0.45 | 1.30 ± 0.42 | <0.001 |
| HMRS | 1.81 ± 0.93 | 1.65 ± 0.86 | 2.12 ± 0.98 | <0.001 |
| RVSWI | 0.27 ± 0.16 | 0.26 ± 0.15 | 0.27 ± 0.18 | 0.63 |
| sRVCPI | 52.65 ± 27.76 | 57.82 ± 29.52 | 42.71 ± 20.82 | <0.001 |
| PAPi | 2.24 ± 1.82 | 2.49 ± 2.03 | 1.77 ± 1.22 | 0.001 |
BMI=body mass index, ICM=ischemic cardiomyopathy, RA pressure=right atrial pressure, RHC=right heart catheterization, PAP=pulmonary artery pressure, PCWP=pulmonary capillary wedge pressure, TR=tricuspid regurgitant, TAPSE=tricuspid annular plane systolic excursions, HMRS=HeartMate Risk Score, RVSWI=right ventricular stroke work index mm Hg/L*m2, sRVCPI=simplified right ventricular contraction pressure index, PAPi=pulmonary artery pulsatility index
Values are shown as absolute numbers (percentages), mean ± SD, or median (IQR).