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. Author manuscript; available in PMC: 2020 Mar 1.
Published in final edited form as: Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2018 Apr 26;11(2):e1523. doi: 10.1002/wnan.1523

Figure 3. Immunization with Escherichia coli outer membrane vesicles protects bacteria-Induced lethality via Th1 and Th17 cell responses.

Figure 3

A. Survival rates of OMV- and sham-immunized mice challenged with E.coli; B. Survival rates of OMV- and sham immunized mice challenged with E. coli 42 d after immunization; C. Serum levels of OMV-reactive IgG; D. OMV-specific production of IFN-g, IL-17,IL-4, and IL-10 from splenic T cells; E. Survival rates of wild-type, IFN-g−/−, IL-17−/−, and IL-4−/− mice after the E. coli injection. (Reprinted with permission from Ref. 71. Copyright © 2013 by The American Association of Immunologists, Inc)