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. Author manuscript; available in PMC: 2020 Mar 1.
Published in final edited form as: Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2018 Apr 26;11(2):e1523. doi: 10.1002/wnan.1523

Figure 8. Bioengineered bacterial outer membrane vesicles as cell-specific drug-delivery vehicles for cancer therapy.

Figure 8

A. Schematic representation of OMVs expressing HER2-specific affibody(AffiHER2OMV) and the application of AffiHER2OMV in cancer therapy; B. Tumor-specific retention and accumulation of delivered siRNA in major vital organs; C.Tumor growth inhibition (TGI) after delivery of siRNA (Reprinted with permission from Ref.125 Copyright © 2014 American Chemical Society)