Table 5.
Dysplasia grade- and DNA ploidy-specific annual transformation rates. Mod = moderate; Sev = severe; Dip = diploid; Tet = tetraploid; An = aneuploid.
| Including transformation within 6 months of index lesion | Excluding transformation within 6 months of index lesion | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| n | Number transformed | Person-years follow up | Annual transformation rate % (95% CI) | n | Number transformed | Person-years follow up | Annual transformation rate % (95% CI) | ||
| Dysplasia grade | No | 121 | 1 | 1045.02 | 0.09 (0.01, 0.68) |
121 | 1 | 1045.02 | 0.09 (0.01, 0.68) |
| Mild | 47 | 2 | 378.85 | 0.53 (0.13, 2.11) |
47 | 2 | 378.85 | 0.53 (0.13, 2.11) |
|
| Mod | 32 | 7 | 187.08 | 3.74 (1.78, 7.85) |
30 | 5 | 186.49 | 2.68 1.11, 6.44 |
|
| Sev | 28 | 13 | 122.13 | 10.64 (6.18, 18.33) |
21 | 7 | 121.29 | 5.77 (2.75, 12.11) |
|
| All | 228 | 23 | 1733.07 | 1.32 (0.88, 1.99) |
219 | 15 | 1731.64 | 0.87 (0.52, 1.44) |
|
| DNA Ploidy | Dip | 183 | 10 | 1478.24 | 0.68 (0.36, 1.26) |
180 | 7 | 1476.69 | 0.47 (0.23, 0.99) |
| Tet | 3 | 0 | 22.68 | 0 | 3 | 0 | 22.68 | 0 | |
| An | 42 | 14 | 234.31 | 5.97 (3.54, 10.1) |
36 | 8 | 232.55 | 3.44 (1.72, 6.88) |
|
| All | 228 | 24 | 1735.23 | 1.38 (0.93, 2.06) |
219 | 15 | 1731.93 | 0.87 (0.52, 1.44) |
|