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. 2018 Oct 26;8:15868. doi: 10.1038/s41598-018-33776-2

Table 2.

Results of mixed model analysis to determine the association between high-gamma activity during the sentence listening period and those during working memory maintenance/scanning operations. The level of significance was set at p-value at ≤ 0.005, invoking Bonferroni correction for multiple comparisons within 10 regions of interest. HG: high-gamma. WM: working memory.

(A) Superior temporal region Estimate (95% CI) t-value p-value (F) Middle frontal region Estimate (95% CI) t-value p-value
HG WM maintenance 0.099 (−0.685 to 0.882) 0.249 0.804 HG WM maintenance 0.110 (−0.067 to 0.288) 1.232 0.220
HG WM scanning −0.649 (−1.239 to −0.059) −2.176 0.031 HG WM scanning 0.110 (−0.037 to 0.257) 1.472 0.143
Hemisphere 0.022 (−0.099 to 0.143) 0.370 0.714 Hemisphere −0.008 (−0.059 to 0.042) −0.352 0.729
Patient age −0.002 (−0.010 to 0.005) −0.708 0.487 Patient age 0.001 (−0.002 to 0.004) 0.725 0.479
(B) Middle temporal region Estimate (95% CI) t-value p-value (G) Inferior frontal region Estimate (95% CI) t-value p-value
HG WM maintenance 0.153 (−0.082 to 0.387) 1.287 0.200 HG WM maintenance 0.072 (−0.287 to 0.431) 0.397 0.692
HG WM scanning 0.067 (−0.139 to 0.272) 0.643 0.521 HG WM scanning 0.049 (−0.193 to 0.290) 0.399 0.690
Hemisphere 0.020 (−0.022 to 0.061) 0.948 0.348 Hemisphere 0.014 (−0.056 to 0.083) 0.405 0.689
Patient age 0.001 (−0.001 to 0.003) 0.765 0.453 Patient age 0.001 (−0.002 to 0.005) 0.765 0.454
(C) Inferior temporal region Estimate (95% CI) t-value p-value (H) Orbitofrontal region Estimate (95% CI) t-value p-value
HG WM maintenance 0.637 (0.362 to 0.913) 4.586 0.000 HG WM maintenance −0.061 (−0.331 to 0.208) −0.453 0.652
HG WM scanning −0.272 (−0.454 to −0.090) −2.961 0.004 HG WM scanning 0.055 (−0.175 to 0.285) 0.474 0.636
Hemisphere 0.031 (−0.015 to 0.077) 1.353 0.184 Hemisphere 0.012 (−0.039 to 0.063) 0.461 0.647
Patient age 0.001 (−0.001 to 0.004) 0.924 0.365 Patient age 0.000 (−0.004 to 0.003) −0.214 0.833
(D) Fusiform region Estimate (95% CI) t-value p-value (I) Inferior precentral region Estimate (95% CI) t-value p-value
HG WM maintenance −0.083 (−0.282 to 0.115) −0.832 0.407 HG WM maintenance 0.293 (0.097 to 0.488) 2.952 0.004
HG WM scanning 0.044 (−0.144 to 0.232) 0.462 0.645 HG WM scanning −0.086 (−0.260 to 0.088) −0.983 0.328
Hemisphere −0.017 (−0.059 to 0.026) −0.803 0.430 Hemisphere 0.015 (−0.061 to 0.091) 0.416 0.682
Patient age 0.000 (−0.002 to 0.002) 0.271 0.790 Patient age 0.006 (0.002 to 0.010) 3.133 0.005
(E) Supramarginal region Estimate (95% CI) t-value p-value (J) Inferior postcentral region Estimate (95% CI) t-value p-value
HG WM maintenance 0.023 (−0.145 to 0.191) 0.272 0.786 HG WM maintenance 0.100 (−0.035 to 0.234) 1.467 0.145
HG WM scanning −0.009 (−0.126 to 0.109) −0.144 0.886 HG WM scanning −0.024 (−0.114 to 0.067) −0.518 0.605
Hemisphere −0.001 (−0.043 to 0.040) −0.071 0.944 Hemisphere 0.007 (−0.033 to 0.048) 0.408 0.691
Patient age 0.001 (−0.001 to 0.003) 1.082 0.294 Patient age 0.003 (0.000 to 0.005) 2.618 0.022