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. 2018 Oct 26;8:15867. doi: 10.1038/s41598-018-34019-0

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Study groups with the initial sample size and vaccination schedules. Fecal samples were collected at two time points: 5–9 days after the injection of either saline or a birth dose of Hep B vaccination (Infant time point), and when animals were 77–88 weeks old (Juvenile time point). The influenza vaccine was given at 6 weeks and then every 12 weeks to mimic the typical pediatric schedule of yearly vaccination but on an accelerated primate schedule. *Indicates vaccines containing thimerosal. Abbr: Hep B, Hepatitis B vaccine; DTaP, Diphtheria, Tetanus, acellular Pertussis vaccine; Rota, rotavirus vaccine; Hib, Haemophilus influenza B vaccine; MMR, Measles Mumps Rubella vaccine; PCV, pneumococcus vaccine; IPV, inactivated polio vaccine; Varicella, chicken pox vaccine; Hep A, hepatitis A vaccine; MCV, meningococcal vaccine.