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. 2018 Oct 26;9(11):1095. doi: 10.1038/s41419-018-1079-7

Fig. 4. Deficiency of Mkk4 or Mkk7 provides moderate RGC protection after CONC.

Fig. 4

a Representative retinal flat mounts stained with cleaved caspase-3 (CASP3) in eyes 5 days after CONC or sham surgery. b Significantly fewer apoptotic cells are present in Mkk4- and Mkk7-deficient animals as compared to WT controls following CONC. N ≥ 4 per genotype per condition; *P ≤ 0.05. c Representative retinal flat mounts stained with TUJ-1 following CONC or sham surgery. d Significantly more cells remain 35 days after CONC in Mkk4- and Mkk7-deficient retinas as compared to WT controls. N ≥ 8 per genotype per genotype and condition. Scale bars: 50 μm. Error bars represent SEM