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. 2018 Oct 26;8:15898. doi: 10.1038/s41598-018-34219-8

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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The first row shows the density reductions in the left hemisphere regarding AL increase in (A) the left precentral gyrus and (B) the left lateral occipital pole. The second row shows reductions in the (C) right pars opercularis. The Y-axis in the scatterplots depicts the standardised residual (regressors: age, sex, and WtHR) of the cluster average volume. The X-axis represents the AL index scores. Please note that correlation coefficients only intend to complement scatterplots visualisation. LH = left hemisphere, RH = right hemisphere, WtHR = waist-to-height ratio.