. Author manuscript; available in PMC: 2018 Oct 27.

Published in final edited form as: J Cardiovasc Pharmacol Ther. 2018 Mar 19;23(4):350–357. doi: 10.1177/1074248418763612

Table 4.

Hemodynamic Parameters (Knockout Study).^a

		Baseline				Reperfusion
	n	HR, bpm	LVDP, cmH₂O	RPP (LVDP × HR)	CF, mL/min	HR, bpm	LVDP, cmH₂O	RPP (LVDP × HR)	CF, mL/min

WT	5	330 ± 10	120 ± 11	39 702 ± 4569	2.4 ± 0.3	286 ± 13	42 ± 10	12 219 ± 3076	1.3 ± 0.2
p53+/−	6	327 ± 11	110 ± 6	35 931 ± 2362	2.1 ± 0.2	293 ± 18	62 ± 5^b	18 241 ± 1979^b	1.4 ± 0.1

Abbreviations: HR, heart rate; LVDP, left ventricular developed pressure; RPP, rate pressure product; CF, coronary flow; WT, wild type, p53^+/−, p53 heterozygous knockout mouse; baseline, 25 minutes after the start of perfusion, reperfusion, 120 minutes after reperfusion.

Data are mean ± SEM.

P < .05 vs WT.