Fig. 4:
diagnostic performance of p16INK4a under receiving operating characteristics/area under the (ROC/AUC) curves. The performance of p16INK4a under ROC/AUC curve to predict high-grade cervical intraepithelial neoplasia and invasive tumour after applying the cut off of 55.28% in all analyzed specimens that resulted in relatively high sensitivity (89.14%), specificity (81.90%), positive predictive value (PPV), (91.20%) and negative predictive value (NPV) (78.18%). CI: confidence interval.