Table 1.
Size and size distribution of drug-loaded micelles measured by dynamic light scattering1
| Number Average Diameter (nm) | Polydispersity Index | |
|---|---|---|
| Effect of CPA:PTX weight ratio (Total drug loading = 5% by weight) | ||
| CPA only | 74.7 ± 1.5 | 0.148 |
| CPA:PTX = 67%:33% | 53.9 ± 5.6 | 0.131 |
| CPA:PTX = 50%:50% | 45.2 ± 4.5 | 0.114 |
| CPA:PTX = 33%:67% | 77.3 ± 11.7 | 0.175 |
| PTX only | 121.3 ± 2.1 | 0.124 |
| Effect of total drug loading (CPA:PTX = 50%:50% by weight) | ||
| 2.5% by weight | 85.5 ± 10.6 | 0.113 |
| 5% by weight | 45.2 ± 4.5 | 0.114 |
| 10% by weight | 65.4 ± 3.1 | 0.110 |
1
Data are presented as mean ± standard error of mean (n = 3).