Table 3.
Outcome of patients according to cumulative fluid balance quartiles
| Variables | CFB quartiles | Total | P for trend | |||
|---|---|---|---|---|---|---|
| Quartile 1 | Quartile 2 | Quartile 3 | Quartile 4 | |||
| Cardiovascular disease | ||||||
| Incident AKI (n, %) | 60 (59.3) | 76 (74.4) | 86 (84.3) | 84 (83.1) | 306 (75.4) | < 0.001 |
| CRRT treatment (n, %)* | 26 (25.7) | 24 (23.5) | 48 (47.1) | 29 (28.7) | 127 (31.3) | 0.114 |
| Days of CRRT before ECMO (days)† | 0 (0–1) | 0 (0–1) | 1 (0–1) | 0 (0–2) | 1 (0–1) | 0.082 |
| ICU LOS (days)†,‡ | 10 (5–16) | 10 (6–18) | 7 (3–14) | 7 (4–14) | 8 (4–15) | 0.014 |
| 90-day mortality (n, %) | 35 (34.7) | 43 (42.2) | 71 (69.6) | 58 (57.4) | 207 (51.0) | < 0.001 |
| Non-cardiovascular disease | ||||||
| Incident AKI (n, %) | 47 (68.1) | 34 (53.1) | 54 (76.1) | 49 (83.1) | 184 (70.0) | 0.011 |
| CRRT treatment (n, %)* | 17 (21.5) | 16 (20.3) | 32 (40.0) | 27 (34.2) | 92 (29.0) | 0.011 |
| Days of CRRT before ECMO (days)† | 1 (0–2) | 1 (1–2) | 2 (1–2) | 1 (1–2) | 3 (1–3) | 0.483 |
| ICU LOS (days)†,‡ | 18 (10–33) | 17 (11–28) | 13 (8–31) | 17 (6–40) | 16 (9–32) | 0.239 |
| 90-day mortality (n, %) | 49 (62.0) | 43 (54.4) | 63 (78.8) | 54 (68.4) | 209 (65.9) | 0.069 |
Abbreviations: AKI Acute kidney injury, CFB Cumulative fluid balance, CRRT Continuous renal replacement therapy, ECMO Extracorporeal membrane oxygenation, ICU Intensive care unit, LOS Length of stay
*Continuous renal replacement therapy imitation during the first 3 days of ECMO commencement
†Data are expressed as median and IQR and compared by Jonckheere-Terpstra test
‡LOS was presented in patients who survived at 30th day from ECMO initiation