Table 4.

Predictive/prognostic value of endocan for ARDS

Predictive value	n	Clinical context	Cutoff point (ng/ml)	AUC	Se	Sp	p	Reference
ARDS onset	48	Polytrauma	<  5.00				0.03	[56]
ARDS onset	175	Sepsis	<  2.50				0.008	[47]
ARDS onset	19	Sepsis	<  3.55	0.92	0.85	1.00	< 0.05	[57]
ARDS onset	72	Sepsis	<  5.49	0.93	1.00	0.77	< 0.001	[58]
28-day mortality	42	ARDS	>  4.96	0.72	0.55	0.86	0.017	[60]
Improving	54	ARDS	<  6.00	0.66	0.85	0.41	< 0.01	[61]
Worsening	42		>  14.0		0.39	0.82

ARDS acute respiratory distress syndrome, AUC area under the curve, Se sensitivity, Sp specificity