Table 1.

Anticancer drugs have different effects on DHA’s cytotoxicity in cancer cells

MTS assay	Cytotoxicity enhanced	Cytotoxicity attenuated	Cytotoxicity unchanged
Initial screen	48	32	21
Validationa	21	20	4

^aOnly 45 drugs available for the validation screen

MDA-MB-231 cells were treated with individual drugs (101 anticancer drugs, the NCI Oncology Set IV) at IC₂₅ and IC₅₀ drug concentrations, and DHA (at 50 μM for initial screen and 25, 50, and 100 μM for validation) for 48 h. Cell viability was determined by MTS assay