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. Author manuscript; available in PMC: 2019 Nov 1.
Published in final edited form as: Biochimie. 2018 Jul 30;154:45–54. doi: 10.1016/j.biochi.2018.07.017

Fig.15.

Fig.15.

Stereo view of the surface diagram of MDH in light green color. The membrane binding segment of MDH is shown as a ribbon in coral color. The superposed corresponding segment in the G81A mutant of MDH-GOX2 in complex with 2-hydroxyoctanoate is shown as a ribbon in pink color. The three α-helixes of the membrane binding region are marked as α1, α2 and α3. The helix-α3 which is predicted to act as a gate for the oxidant is away from the channel in the G81A complex, while blocking it in MDH. The FMN and 2-hydroxyoctanoate are shown as ball and stick and in black and red colors respectively.