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. Author manuscript; available in PMC: 2019 Nov 1.
Published in final edited form as: Hepatology. 2018 Oct 9;68(5):1726–1740. doi: 10.1002/hep.30071

Figure 2. Baicalein inhibits stemness in liver TICs.

Figure 2

A) Analyses of BC and its derivatives on expression patterns of self-renewal and differentiation genes after 24 hr of treatment. B) Effects of BC on self-renewal of TICs in methylcellulose-based spheroid formation assay after 7 days of treatment. Scale bars represent 400 μm. C) Q-PCR measurement of CD133 mRNA in TICs treated with BC, CCI779 and both for 24 hr. D) RT-PCR measurement of CD133 mRNA in Huh7 treated with BC, CCI779 and both for 18 hr. Error bars are SEM of three replicate treatments. Statistical comparison was performed by One-way ANOVA with Bonferroni post-test. *p<0.05 and **p<0.01.