Table 1.
Characteristics | Responders [n=9] |
Virological Breakthrough [n=4] |
---|---|---|
Mean Age (Range, Years) | 58 (39–75) | 63 (53–70) |
Female (%) | 3 (33) | 3 (75) |
Race (%) | ||
White | 5 (56) | 2 (50) |
African-American | 3 (33) | 1 (25) |
Asian | 1 (11) | 1 (25) |
IL28B rs12979860 Genotype | ||
CC | 1 | 0 |
CT or TT | 8 | 4 |
IFNL4 rs368234815 Genotype | ||
TT/TT | 1 | 0 |
TT/ΔG | 7 | 3 |
ΔG/ΔG | 1 | 1 |
Mean ALT (Range, U/L) | 80 (37–172) | 75 (47–122) |
Mean AST (Range, U/L) | 67 (21–190) | 55 (38–66) |
HCV RNA log10(mean, IU/mL) | 6.6 | 7.0 |
Ishak Fibrosis Score | ||
0–2 | 3 (33) | 1 (25) |
3–4 | 4 (45) | 0 (0) |
5–6 | 2 (22) | 3 (75) |