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. 2018 Oct 14;2018:9232065. doi: 10.1155/2018/9232065

Figure 5.

Figure 5

SPR reduced cardiac inflammation in DCM. (a) Representative immunohistochemical micrographs of cardiac tissue stained with TNF-α and F4/80 for NDC, STZ + NS, and STZ + SPR groups, respectively (original magnification 20×). (b) The IHC scores of heart sections for TNF-α IHC staining. (c) The percentage of positive staining per section for F4/80 IHC staining. (d, e) Gene expression of TNF-α and MCP-1 for these three groups, respectively. N = 8, data are shown as means ± SEM. ∗P<0.05, ∗∗P<0.01, and ∗∗∗P<0.001 vs. NDC group; ##P < 0.01 and ###P < 0.001 vs. STZ + NS group.