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SPR restored the mitochondria contents and improved myocardial energy metabolism in diabetic rats. (a–e) Gene expression of Eral1, ATP5α1, COX5b, Sirt1, and PGC-1α for NDC, STZ + NS, and STZ + SPR groups. N = 8, data are shown as means ± SEM. ∗P < 0.05, ∗∗P < 0.01, and ∗∗∗P < 0.001 vs. NDC group; #P < 0.05 and ##P < 0.01 vs. STZ + NS group.
