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. Author manuscript; available in PMC: 2019 Nov 1.
Published in final edited form as: Trends Biochem Sci. 2018 May 4;43(11):854–857. doi: 10.1016/j.tibs.2018.04.006

Figure 2. Roles of FAO in Cell Fate Determination.

Figure 2

(A) FAO in endothelial cell fate determination. SNAIL is an EndoMT marker and VEGFR3 is a lymphatic gene. (B) FAO in immune cell fate determination. (C) FAO in cancer cell fate determination. Abbreviations: Ac, acetylation; Acetyl-CoA, acetyl coenzyme A; ACLY, ATP citrate lyase; ACSS2, acyl-coenzyme A synthetase short-chain family member 2; AMPK, AMP-activated kinase; CPT, carnitine palmitoyltransferase; FAO, fatty acid oxidation; mTOR, mechanistic target of rapamycin; P, phosphorylation; PD-1, programmed cell death 1; PROX1, prospero homeobox 1; TCA, tricarboxylic acid; TGF-β, transforming growth factor β; TRAF6, tumor necrosis factor receptor-associated factor 6.