Table 1.
Demographic and clinical characteristics of participants
| TRS | RCS | EES | Control | P value* | P value** | |
|---|---|---|---|---|---|---|
| Number | 87 | 98 | 53 | 38 | ||
| Age (years) | 49.2 ± 1.5 | 52.6 ± 1.3 | 51.4 ± 2.0 | 47.6 ± 3.2 | 0.142 | 0.221 |
| Male:female | 46:41 | 42:56 | 16:37 | 18:20 | 0.069 | 0.031 |
| BMI (kg/m2) | 24.4 ± 3.8 | 23.1 ± 2.8 | 24.5 ± 3.4 | 21.8 ± 3.2 | 0.017 | 0.11 |
| RE | 37 (43%) | 24 (25%) | 13 (24%) | – | – | 0.015 |
| Endoscopy negative and AET > 4.2% (NERD) | 27 (31%) | 21 (21%) | 11 (21%) | – | – | 0.237 |
| Endoscopy negative and AET < 4.2% (RH and FH) | 23 (26%) | 53 (54%) | 29 (55%) | – | – | <0.001 |
| AET > 4.2% | 55 (63%) | 38 (39%) | 20 (38%) | 5 (13%) | 0.001 | 0.001 |
BMI, body mass index; EES, extraesophageal syndrome; FH, functional heartburn; NERD, non-erosive reflux disease; RCS, reflux chest pain syndrome; RE, reflux esophagitis; RH, reflux hypersensitive; TRS, typical reflux syndrome
*P value, comparison of TRS, RCS, EES and controls by one-way ANOVA;
**P value, comparison of TRS, RCS, EES by one-way ANOVA. Data are expressed as mean ± SE and number (%).