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Gene expression changes in T-cell-transfer colitic mice after BI119 treatment. IL17A, IL17F, IL22, IFNG and S100A8 expression was reduced in BI119-treated colitic mice. IL10 expression was not altered using this treatment. Messenger RNA expression was assessed by real-time polymerase chain reaction. Mean ± SEM. ns > 0.05, *P ≤ 0.05, **P < 0.005, ****P < 0.0001 compared to CD45+RBhigh mice.
