Table 3.
Clinical characteristics of 40 families in whom disease-causing mutations were identified compared to those in whom no causative mutation was found.
| Characteristic | Mutation n(%) | No mutation n(%) | p-value |
|---|---|---|---|
| Sex | 0.23 | ||
| Male | 17 (18.5) | 75 (81.5) | |
| Female | 23 (25.8) | 66 (74.2) | |
| Race | 0.09 | ||
| White, non-hispanic | 28 (26.4) | 78 (73.6) | |
| Other | 12 (16.0) | 63 (84.0) | |
| Family history | < 0.00001 | ||
| Yes | 34 (39.5) | 52 (60.5) | |
| No | 6 (6.3) | 89 (93.7) | |
| Histopathology | 0.61 | ||
| MCD | 5 (19.2) | 21 (80.8) | |
| FSGS | 26 (23.9) | 83 (76.1) | |
| Sample origin | 0.52 | ||
| US | 32 (21.3) | 118 (78.7) | |
| Non-US | 8 (26.7) | 22 (73.3) |