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. 2018 Oct;7(5):599–608. doi: 10.21037/tlcr.2018.08.03

Table 2. Summarized survival outcomes based on perioperative chemotherapy and cytoreduction (adapted from reference 24).

Variable No. of studies     Mortality rate Expected 1-year survival [%] Expected 5-year survival [%]
Entire cohort 20     0.17 (0, 0.39) 84 [68–100] 42 [14–100]
EPIC used
   Yes 7     0.16 (0, 0.44) 85 [64–100] 45 [11–100]
   No 13     0.19 (0, 0.55) 83 [58–100] 39 [6–100]
Chemotherapy agents used
   Mitomycin-C only 1     0.24 78 30
   Cisplatin only 3     0.14 87 49
   Doxorubicin + cisplatin 3     0.23 79 32
   Docetaxel + cisplatin 1     0.35 70 17
   Drug combinations including doxorubicin, mitomycin-C, cisplatin 11     0.16 85 45
Number of patients in a study
   <100 17     0.20 82 37
   >100 3     0.15 86 47
Median PCI score reported
   <19 4     0.16 85 45
   >19 16     0.17 84 42
Median no. of patients undergoing complete cytoreduction
   <50% 6     0.18 84 41
   ≥50% 14     0.16 85 45

EPIC, early postoperative intraperitoneal chemotherapy; PCI, peritoneal cancer index.