| General information on enzymes |
| BRENDA |
https://www.brenda-enzymes.org/ |
Molecular and biochemical information on enzymes |
| KEGG |
https://www.genome.jp/kegg/ |
Computational representation of pathways |
| MetaCyc |
https://metacyc.org/ |
Metabolic pathways and enzymes |
| EC2PDB |
https://www.ebi.ac.uk/thornton-srv/databases/enzymes/ |
Known enzyme structures that have been deposited in the Protein Data Bank (PDB) |
| FunTree |
https://www.ebi.ac.uk/thornton-srv/databases/FunTree/ |
Evolution of enzyme function within domain super families |
| Feature-specific databases |
| Recon3D/VMH |
http://vmh.life |
Human metabolic network reconstruction with pharmacogenomic associations, phenotypic data, and structural information for proteins and metabolites |
| STRENDA |
https://www.beilstein-strenda-db.org/strenda/ |
Repository of functional enzymology data |
| SABIO-RK |
sabio.h-its.org |
Information about biochemical reactions and kinetic rate equations |
| ASD (allosteric database) |
http://mdl.shsmu.edu.cn/ASD/ |
Resource for structure, function, disease, and related annotation for allosteric macromolecules and modulators |
| MACiE |
https://www.ebi.ac.uk/thornton-srv/databases/MACiE/ |
Database for enzyme reaction mechanisms |
| eQuilibrator |
http://equilibrator.weizmann.ac.il/ |
Thermodynamics calculator for biochemical reactions |
| ORENZA |
http://www.orenza.u-psud.fr/ |
Enzyme activities for which no sequences are available in the main sequence protein databases |
| Nomenclature databases |
| IUBMB |
https://iubmb.org/ |
Assignment of EC numbers |
| ExplorEnz |
https://www.enzyme-database.org/ |
Interface for enzyme nomenclature |
| IntEnz |
https://www.ebi.ac.uk/intenz/ |
Contains recommendations of IUBMB on the classification of enzyme-catalyzed reactions |
| ENZYME |
https://enzyme.expasy.org |
Information relative to the nomenclature of enzymes |
| Databases of enzyme classes |
| MEROPS |
https://www.ebi.ac.uk/merops/ |
Database for proteinases |
| REBASE |
http://rebase.neb.com/rebase/ |
Database of information about restriction enzymes and DNA methyltransferases |
| CAZy |
http://www.cazy.org/ |
Classification of enzymes involved in the synthesis, metabolism, and transport of carbohydrates |
| PeroxiBase |
peroxibase.toulouse.inra.fr/ |
Centralization and annotation of most of the peroxidase superfamilies |
| ESTHER |
http://bioweb.ensam.inra.fr/ESTHER/general |
Database for α/β-hydrolases |
| HCS |
www.enzyme.chem.msu.ru/hcs/ |
Hierarchical classification of catalytic sites of hydrolases |
| PTM enzyme database |
| PTP |
http://ptp.cshl.edu/ |
Database for protein tyrosine phosphatases |
| EKPD |
http://ekpd.biocuckoo.org/ |
Kinase and phosphatase database |
| KinBase |
kinase.com/web/current/kinbase/ |
Includes kinomes, classification, disease association, and an extensive database of protein kinase genes |
