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Cancer cachexia is associated with increased Serpina3n in skeletal muscle and in circulation. Serpina3n mRNA levels (A) and protein abundance (B) in gastrocnemius muscles of cachectic and CTR mice. (C) Serpina3n protein levels in circulation of cachectic and CTR mice. For western‐blotting, 20 μg of proteins were loaded in each lane for each sample. Results are means ± SE (n = 8/group). Statistical analysis was performed using unpaired t‐test (*** P < 0.001 vs. CTR).
