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Differences in B. pseudomallei lipid A structure affect binding strength to human LBP. Surface plasmon resonance was used to measure the binding rate constants between 1026b LPS and hLBP (A), 576a LPS and hLBP (B), and Salmonella Minnesota LPS and hLBP (C). Data shown are the raw data average of triplicate experiments. Colored lines represent different concentrations of hLBP, as indicated. Arrows indicate hLBP injection start and injection stop points.
