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B. pseudomallei lipid A structure. The structures and modifications are based on lpxO and pagL mutant analysis from a detailed dissection of the literature and this work. Blue residues are Ara4N that are nonstoichiometric, and the orange residue is the phosphate group that is absent in monophosphorylated lipid A. The red hydroxyl group indicates the LpxO modification, and the red acyl chain indicates the PagL modification.
