FIG 1.

Immunochip genotyping and association analysis. (A) Manhattan plot of the GWAS. Negative log₁₀ P values for tonsillitis association across all autosomes. The strongest association signals were identified at 31 to 31.5 Mb on chromosome 6 (rs28732081; OR, 4.7; P = 5.7 × 10⁻⁶). (B) Manhattan plot of the negative log₁₀ P values on chromosome 6. The major histocompatibility complex locus at 29 to 32 Mb on chromosome 6 is highlighted in green. Blue line, suggestive association; red line, genome-wide association.