Table 6.

Relative Gene Expression (RQ Value ± SD) in Kidneys for Experiments Using 6 UOG Chemicals Using L13 as Endogenous Control Gene

Genes	Uninfecteda	p values	3 dpi FV3b	p values	p values Uninf/3 dpic
GCSFR	C: 276 ± 290		C: 1107 ± 1502		C: NS
	L: 102 ± 89	NS	L: 186 ± 250	NS	L: NS
	H: 2240 ± 3921	NS	H: 1114 ± 1048	NS	H: NS
IFN type I	C: 178 ± 162		C: 2715 ± 3419		C: 0.01
	L: 274 ± 231	NS	L: 107 ± 116	0.001	L: NS
	H: 204 ± 363	NS	H: 199 ± 389	0.01	H: NS
IFN type III (λ)	C: 415 ± 444		C: 470 ± 536		C: NS
	L: 170 ± 227	NS	L: 252 ± 354	NS	L: NS
	H: 521 ± 224	NS	H: 33 ± 37	NS	H: NS
IL-1β	C: 60 ± 76		C: 157 ± 166		C: NS
	L: 33 ± 23	NS	L: 192 ± 218	NS	L: NS
	H: 131 ± 156	NS	H: 14 ± 8	0.003	H: NS
IL-10	C: 33 ± 50		C: 268 ± 58		C: NS
	L: 4 ± 6	NS	L: 620 ± 543	NS	L: 0.02
	H: 103 ± 139	NS	H: 34 ± 46	NS	H: NS
IL-34	C: 3 ± 2		C: 53 ± 53		C: 0.04
	L: 1 ± .1	NS	L: 20 ± 16	NS	L: NS
	H: 11 ± 5	NS	H: 63 ± 47	NS	H: NS
CSF-1R	C: 17 ± 10		C: 211 ± 273		C: 0.06
	L: 6 ± 6	NS	L: 105 ± 125	NS	L: 0.02
	H: 416 ± 697	0.03	H: 366 ± 556	NS	H: NS
TNF-α	C: 1859 ± 3409		C: 127659 ± 174670		C: 0.02
	L: 4269 ± 4709	NS	L: 64516 ± 79618	NS	L: NS
	H: 4704 ± 5643	NS	H: 2881 ± 2635	0.06	H: NS

NS, nonsignificant; *,significant.

^aGene expression RQ values from kidneys of tadpoles (10 per group) treated with 0.2% EtOH, 0.1 μg/l (L), or 1 μg/l (H) of UOG mixture for 3 weeks using L13 as reference gene. p value determined between vehicle control and treated animals.

^bGene expression RQ values from kidneys of tadpoles (10 per group) treated with 0.2% EtOH, 0.1 μg/l (L), or 1 μg/l (H) of UOG mixture then FV3 infected for 3 days using L13 as reference gene. p value determined between vehicle control and treated animals.

^cp value determined by between each treated and corresponding infected group.