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. 2018 Aug 23;10(7):979–991. doi: 10.1080/19420862.2018.1501252

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© 2018 The Author(s). Published by Taylor & Francis

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.

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Figure 7. — Comparison of anti-β-WTA antibodies to their germline sequences. Alignment of the (A) 4462, (B) 6078, and (C) 4497 light and heavy chain Fab sequences to their respective germline sequences. Antibody light chain CDRs are labeled in purple, and heavy chain CDRs labeled in blue. Amino acids changed from the germline are boxed in black with white lettering. CDR amino acids that contact the WTA epitope (4.5Å cutoff) are boxed in yellow. Germlines matches for antibodies 4462, 6078 and 4497 were determined using the IMGT/V-QUEST server (http://www.imgt.org).