Table 1.
Characteristics of the included studies
| Year | Authors | Group (n) | Age (years) (mean or median) | BMI (kg/m2)/weight (kg) (mean or median) | Surgery | Anesthesia | Blocking time | Block solution | Pain assessment | Primary outcome |
|---|---|---|---|---|---|---|---|---|---|---|
|
| ||||||||||
| 2008 | Carney et al7 | TAP: 24, Sham: 26 | TAP: 54, Sham: 50 | TAP: 26, Sham: 27 | TAH | GA | Pre | 0.75% RP (1.5 mg/kg) | VAS (10) | MC |
| 2011 | Amr and Amin21 | TAP (pre): 23, TAP (post): 23, Sham: 22 | TAP (pre): 54, TAP (post): 52 Sham: 51 | TAP (pre): 80, TAP (post): 82, Sham: 82 | TAH | GA | Pre and post | 0.375% BP (20 mL) | VAS (100) | MC |
| 2011 | Atim et al22 | TAP: 18, Sham: 18, INF: 19 | TAP: 47, Sham: 44, INF: 40 | TAP: 71, Sham: 67, INF: 65 | TAH | GA | Post | 0.25% BP (20 mL) | VAS (10) | PP |
| 2011 | De Oliveira et al23 | TAP (0.25% RP): 21, TAP (0.5% RP): 22, Sham: 23 | TAP (0.25% RP): 46, TAP (0.5% RP): 45, Sham: 47 | TAP (0.25% RP): 27, TAP (0.5% RP): 25, Sham: 27 | LH | GA | Pre | (0.25%–0.5%) RP (20 mL) | NRS (10) | QoR-40 |
| 2012 | Kane et al10 | TAP: 28, NC: 28 | TAP: 46, NC: 44 | TAP: 31, NC: 30 | LH | GA | Pre | 0.5% RP+EP (20 mL) | VAS (100) | QoR-40 |
| 2013 | Gharaei et al24 | TAP: 21, NC: 21 | TAP: 64, NC: 65 | TAP: 71, NC: 72 | TAH | GA | Post | 0.2% RP (0.5 mg/kg) | VAS (10) | PP |
| 2014 | Bhattacharjee et al25 | TAP: 45, Sham: 45 | TAP: 46, Sham: 45 | TAP: 53, Sham: 53 | TAH | GA | Pre | 0.25% BP (0.5 mL/kg) | VAS (100) | PP |
| 2014 | Calle et al26 | TAP: 100, Sham: 97 | TAP: 44, Sham: 43 | TAP: 25, Sham: 26 | LH | GA | Post | 0.25% BP (20 mL) | VAS (10) | PP |
| 2014 | Marais et al27 | TAP: 15, Sham: 15 | TAP: 47, Sham: 48 | TAP: 25, Sham: 28 | TAH | GA | Pre | 0.25% BP (20 mL) | VAS (10) | MC |
| 2015 | Røjskjaer et al28 | TAP: 23, Sham: 23 | TAP: 49, Sham: 47 | TAP: 28, Sham: 25 | TAH | GA | Pre | 0.75% RP (20 mL) | VAS (100) | MC |
| 2015 | Torup et al29 | TAP: 34, Sham: 31 | TAP: 53, Sham: 57 | TAP: 24, Sham: 29 | RH | GA | Pre | 0.5% RP (20 mL) | VAS (100) | MC |
| 2016 | Ghisi et al11 | TAP: 22, NC: 22 | TAP: 46, NC: 48 | TAP: 59, NC: 61 | LH | GA | Pre | 0.375% LBP (20 mL) | NRS (10) | MC |
| 2016 | Moyo et al30 | TAP+Dxm: 16, Sham: 16 | TAP+Dxm: 41, Sham: 47 | TAP+Dxm: 24, Sham: 24 | AH | GA | Pre | 0.25 % BP (20 mL), Dxm (4 mg) | VAS (10) | PP |
Abbreviations: AH, abdominal hysterectomy; BP, bupivacaine; Dxm, dexamethasone; EP, epinephrine; GA, general anesthetic; INF, surgical site infiltration; LBP, levobupivacaine; LH, laparoscopic hysterectomy; MC, morphine consumption; NC, no block; PP, postoperative pain; Post, postoperation; Pre, preoperation; QoR-40, quality of recovery score; RH, robotic-assisted hysterectomy; RP, ropivacaine; SA, spinal anesthesia; Sham, sham block; TAH, total abdominal hysterectomy, TAP, transversus abdominis plane block; VAS, visual analogue scale; NRS, numerical rating scale.