Table 1.
The frequency of ALK mutations in NB
| Author, year | Number of NB samples | Frequency of ALK mutations | |
|---|---|---|---|
| Mossé et al, 2008 | 167 (high-risk NB samples) | Total | 8.4% (14/167) |
| Janoueix-Lerosy et al, 2008 | 115 | Total | 6.1% (7/115) |
| F1174 | 14.3% (1/7) | ||
| R1275 | 71.4% (5/7) | ||
| Other | 14.3% (1/7) | ||
| Chen et al, 2008 | 215 | Total | 6.1% (13/215) |
| F1174 | 50% (7/14) | ||
| R1275 | 35.7% (5/14) | ||
| Other | 14.3% (2/14) | ||
| de Brouwer et al, 2010 | 254 | Total | 6.7% (17/254) |
| F1174 | 29.4% (5/17) | ||
| R1275 | 58.8% (10/17) | ||
| Other | 11.8% (2/17) | ||
| George et al, 2008 | 93 | Total | 7.5% (7/93) |
| F1174 | 57.1% (4/7) | ||
| R1275 | 14.3% (1/7) | ||
| Other | 28.6% (2/7) | ||
| Pugh et al, 2013 | 240 | Total | 9.2% (22/240) |
| Bellini et al, 2015 | 277 | Total | 9.7% (27/277) |
| F1174 | 55.5% (15/27) | ||
| R1275 | 44.4% (12/27) | ||
| Bresler et al, 2014 | 1,596 | Total | 8% (126/1,596) |
| F1174 | 30% (38/126) | ||
| R1275 | 43% (54/126) | ||
| Others | 27% (34/126) | ||
Abbreviation: NB, neuroblastoma.