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The simulation model of Su(dx) 12LHECT. A, ribbon diagram of the structural model of Su(dx) 12LHECT generated by SwissModel using Itch (PDB code 5XMC) as the template. The coloring is the same as in Fig. 1A. The mutation residues are displayed as spheres. B and C, autoubiquitination assay of Su(dx) WT and various mutants. Ubiquitination efficiencies were normalized to those of Su(dx) WT and were plotted as the mean ± S.D. (error bars) of the triplicate experiments.
