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. 2018 May 16;75(8):593–603. doi: 10.1136/oemed-2017-104944

Table 1.

Group 1 agents evaluated in the IARC Monographs Volumes 1–120, excluded from primary list of occupational carcinogens

Agent Volume (a) Year (a) Cancers with sufficient evidence in humans (b)
Reason for Exclusion: Group 1 classification based on mechanistic upgrade
Ethylene oxide 60 1994 N/A
2,3,4,7,8-Pentachlorodibenzofuran 100F 2012 N/A
3,4,5,3’,4’-Pentachlorobiphenyl (PCB-126) 100F 2012 N/A
4,4'-Methylenebis(2-chloroaniline) (MOCA) 99 2010 N/A
Benzidine, dyes metabolized to 99 2010 N/A
Benzo(a)pyrene 92 2010 N/A
Neutron radiation 75 2000 N/A
Reason for Exclusion: Evaluation did not include occupational epidemiology data
Aflatoxins Sup 7 1987 Liver
Erionite Sup 7 1987 Mesothelioma
Fission products, including strontium-90 100D 2012 Salivary gland, oesophagus, stomach, colon, lung, bone, basal cell of the skin, female breast, kidney, urinary bladder, brain and CNS, thyroid, leukaemia
Fluoro-edenite fibrous amphibole 111 2017 Mesothelioma
Reason for Exclusion: Group 1 classification is for an occupation, industry, or process
Acheson process, occupational exposure associated with 111 2017 Lung
Aluminium production Sup 7 1987 Lung, bladder
Auramine production Sup 7 1987 Bladder
Coal gasification Sup 7 1987 Lung
Coal-tar distillation 92 2010 Skin
Coke production Sup 7 1987 Lung
Haematite mining (underground, with exposure to radon)(c) Sup 7 1987 Lung
Iron and steel founding (occupational exposure during) Sup 7 1987 Lung
Isopropyl alcohol manufacture using strong acids Sup 7 1987 Nasal cavity
Magenta production Sup 7 1987 Bladder
Painter (occupational exposure as a) 47 1989 Lung, mesothelioma, bladder
Rubber manufacturing industry (occupational exposures in) Sup 7 1987 Leukaemia, lymphoma, lung, stomach, bladder