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Hospitalisations and pulmonary exacerbations, 2014 ivacaftor and comparator cohorts, (A) USA and (B) UK. ªHospitalisation due to any reason in the US CFFPR and for PEx in the UK CFR. bIn the UK CFR, PEx were defined as the requirement of intravenous antibiotic use at home or in the hospital. CFFPR, Cystic Fibrosis Foundation Patient Registry; CFR, Cystic Fibrosis Registry; PEx, pulmonary exacerbations; RR, relative risk.
