Figure 2.

(A) Hospitalisations and (B) PEx by age and lung function, 2014 ivacaftor and comparator cohorts, USA and UK. Error bars indicate 95% CIs. *P=0.23; ^†p=0.12. Hospitalisation due to any reason in the US CFFPR and for PEx in the UK CFR; PEx were defined as the requirement of intravenous antibiotic use at home or in the hospital. CFFPR, Cystic Fibrosis Foundation Patient Registry; CFR, Cystic Fibrosis Registry; PEx, pulmonary exacerbations; ppFEV₁, per cent predicted FEV ₁. Refer to online supplementary tables S1-S4 for tables corresponding to figure 2.