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. 2018 Aug 24;7(11):e1509821. doi: 10.1080/2162402X.2018.1509821

Figure 2.

Figure 2.

Immunization with AGI-101H significantly increases the frequency of ALDH1-specific CD8+ T cells. A. Representative analysis of ALDH1-specific CD8+ T cells in melanoma patient immunized with the AGI-101H vaccine. B. Cytometric data of multiparametric analysis of the frequency of ALDH1-specific CD8+ T cells performed before and after administration of single dose of AGI-101H vaccine were statistically analyzed using Wilcoxon matched-pairs signed rank test. ****p < 0.0001. Data are presented as dot plots with mean shown as a line. C. Cytometric data obtained for healthy controls (n = 10), untreated patients divided into patients with stage II-III (n = 7) and patients with stage IV (n = 17), AGI-101H-vaccinated patients (n = 39) at day 0 and at day 6, were statistically analyzed using Kruskal-Wallis test, p < 0.0001. Differences between groups were tested using Mann Whitney U test: ****p < 0.0001, ***p = 0.002, **p = 0.007, *p = 0.03. Data are presented as dot plots with mean shown as a line.