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. 2018 Aug 24;7(11):e1509821. doi: 10.1080/2162402X.2018.1509821

Figure 3.

Figure 3.

ALDH1A1-specific peripheral CD8+ T lymphocytes from vaccinated melanoma patients acquire Central Memory T cell phenotype (CM). A. Flow cytometry analysis of CD45RA and CCR7 cell surface markers on peripheral CD8+ T lymphocytes (not specific for ALDH1A1 (LLYKLADLI) peptide). Representative plots from AGI-101H vaccinated melanoma patient at day 0 and day 6 after vaccination are depicted. B. Percentage of defined peripheral CD8+ T cell subpopulations not specific for ALDH1A1 (LLYKLADLI) peptide in AGI-101H treated melanoma patients on the day of vaccine administration (day 0) and 6 days later. C. Flow cytometry analysis of CD45RA and CCR7 cell surface markers on peripheral CD8+ T lymphocytes specific for ALDH1A1 (LLYKLADLI) peptide. Representative plots from AGI-101H vaccinated melanoma patient at day 0 and day 6 after vaccination are depicted. D. Percentage of defined peripheral CD8+ T cell subpopulations specific for ALDH1A1 (LLYKLADLI) peptide in AGI-101H treated melanoma patients on the day of vaccine administration (day 0) and 6 days later. CM – Central Memory, EM – Effector Memory, N – Naive, EFF – Effector; **p < 0.005.