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. 2018 Aug 23;7(11):e1502128. doi: 10.1080/2162402X.2018.1502128

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© 2018 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.

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Figure 2. — Prognostic value of TIM-3, PD-1 and LAG-3+ iTILs co-infiltration among ER- breast cancer patients. Kaplan Meier curve of breast cancer-specific survival among ER- breast cancer patients stratified by the presence or absence of one or more immune checkpoint markers is shown with corresponding number of patients, events and a log rank p value. Blue: All negative (TIM3-/PD1-/LAG3-), green: Single positive (TIM3+ or PD1+ or LAG3+), grey: Double positive (TIM3+/PD1+ or TIM3+/LAG3+ or PD1+/LAG3+), purple: All positive (TIM3+/PD1+/LAG3+).