Table 2.
Reintervention in the First Year After Initial UF Procedure
| Myomectomy (of known type) | Abdominal myomectomy | Hysteroscopic myomectomy | Laparoscopic myomectomy | EA | UAE | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| n = 13,804 | n = 8,018 | n = 941 | pa | n = 4,845 | pa | n = 17,198 | pb | n = 4,629 | pb | |
| Reintervention in the first year after initial procedure | ||||||||||
| Reintervention, n (%)c | 560 (4.1) | 244 (3.0) | 113 (12) | <0.0001 | 203 (4.2) | 0.0006 | 2,139 (12.4) | <0.001 | 324 (7.0) | <0.001 |
| Days to reintervention, mean (SD) | 149 (108.6) | 172 (111.2) | 117 (101.1) | <0.0001 | 138 (103.8) | 0.0011 | 158 (107.4) | 0.017 | 175 (115.9) | <0.001 |
| Cumulative proportion of patients undergoing reintervention, n (%) | ||||||||||
| 1 month | 89 (1) | 25 (0) | 24 (3) | <0.0001 | 40 (1) | <0.0001 | 235 (1.4) | <0.001 | 54 (1.2) | <0.001 |
| 3 months | 210 (2) | 77 (1) | 56 (6) | <0.0001 | 77 (2) | 0.0015 | 745 (4.3) | <0.001 | 105 (2.3) | 0.003 |
| 6 months | 360 (3) | 140 (2) | 87 (9) | <0.0001 | 133 (3) | 0.0001 | 1,273 (7.4) | <0.001 | 162 (3.5) | 0.007 |
| 9 months | 463 (3) | 184 (2) | 100 (11) | <0.0001 | 179 (4) | <0.0001 | 1,716 (10.0) | <0.001 | 239 (5.2) | <0.001 |
| 12 months | 560 (4) | 244 (3) | 113 (12) | <0.0001 | 203 (4) | 0.0006 | 2,139 (12.4) | <0.001 | 324 (7.0) | <0.001 |
| No. of reinterventions, n (%) | ||||||||||
| 0 | 13,244 (95.9) | 7,774 (97.0) | 828 (88.0) | <0.0001 | 4,642 (95.8) | 0.0006 | 15,059 (87.6) | <0.001 | 4,305 (93.0) | <0.001 |
| 1 | 545 (3.9) | 238 (3.0) | 109 (11.6) | <0.0001 | 198 (4.1) | 0.0007 | 2,035 (11.8) | <0.001 | 303 (6.5) | <0.001 |
| 2 | 13 (0.1) | 5 (0.1) | 4 (0.4) | <0.0001 | 4 (0.1) | 0.6746 | 97 (0.6) | <0.001 | 13 (0.3) | 0.015 |
| >2 | 2 (0.0) | 1 (0.0) | 0 (0.0) | 0.7319 | 1 (0.0) | 0.7188 | 7 (0.0) | 0.157 | 8 (0.2) | <0.001 |
| First reintervention procedure, n (% of patients with reintervention) | ||||||||||
| Hysterectomy | 209 (37) | 79 (32) | 52 (46) | <0.0001 | 78 (38) | 0.0018 | 1,383 (65) | <0.001 | 186 (57) | <0.001 |
| Myomectomy | 110 (20) | 52 (21) | 10 (9) | 0.1471 | 48 (24) | 0.0323 | 196 (9) | 0.004 | 43 (13) | 0.460 |
| Abdominal | 47 (8) | 32 (13) | 3 (3) | 0.8253 | 12 (6) | 0.1615 | 88 (4) | 0.0056 | 18 (6) | 0.5570 |
| Hysteroscopic | 9 (2) | 4 (2) | 3 (3) | 0.0030 | 2 (1) | 0.8341 | 30 (1) | 0.0031 | 13 (4) | 0.0002 |
| Laparoscopic | 49 (9) | 102 (42) | 4 (4) | 0.0379 | 33 (16) | <0.0001 | 65 (3) | 0.4281 | 7 (2) | 0.0357 |
| Unknown | 5 (1) | 11 (5) | 0 (0) | 0.5127 | 1 (0) | 0.4195 | 13 (1) | 0.1079 | 5 (2) | 0.0616 |
| EA | 244 (40) | 102 (42) | 47 (42) | <0.0001 | 75 (37) | 0.1932 | 498 (23) | <0.001 | 56 (17) | 0.034 |
| UAE | 17 (3) | 11 (5) | 4 (4) | 0.0410 | 2 (1) | 0.0972 | 62 (3) | <0.001 | 39 (12) | <0.001 |
| MRgFUS | 0 (0) | 0 (0) | 0 (0) | 1.0000 | 0 (0) | 1.000 | 0 (0) | 1.000 | 0 (0) | 1.000 |
Source: Truven MarketScan Commercial Claims and Encounters data for 2008–2014.
Outcomes evaluated in the 12 months after the initial UF-related procedure for each patient.
a
Wilcoxon rank-sum tests and chi-squared tests were used to compare continuous and categorical variables, respectively.
b
All comparisons are relative to the myomectomy cohort.
c
Based on unique service dates of claims with a procedure code for UF-related intervention. To account for delays in claims processing and coding related to follow-up care, a procedure within 2 weeks of the prior procedure, and of the same procedure type was not considered a reintervention.
MRgFUS, magnetic resonance-focused ultrasound.