Table 3.
Risk of Reintervention Associated with the Initial Intervention and Other Factors
| Model of any reintervention with myomectomy of known type | Model of any reintervention with myomectomy subtypes | |||
|---|---|---|---|---|
| n = 35,631 | HR | 95% CI | HR | 95% CI |
| Initial procedure (reference: myomectomy of known type) | (Reference: abdominal myomectomy) | |||
| Hysteroscopic myomectomy | — | — | 2.79 | 2.36–3.29 |
| Laparoscopic myomectomy | — | — | 1.25 | 1.11–1.41 |
| EA | 2.63 | 2.44–2.83 | 3.23 | 2.94–3.54 |
| UAE | 1.56 | 1.42–1.72 | 1.89 | 1.69–2.11 |
| Demographics | ||||
| Age group (reference: 18–29) | ||||
| 30–34 | 1.30 | 1.08–1.56 | 1.29 | 1.08–1.55 |
| 35–39 | 1.38 | 1.16–1.64 | 1.35 | 1.14–1.61 |
| 40–44 | 1.35 | 1.13–1.60 | 1.30 | 1.09–1.54 |
| 45–49 | 1.04 | 0.87–1.23 | 0.99 | 0.83–1.18 |
| Geographic region (reference: South) | ||||
| Northeast | 0.98 | 0.91–1.06 | 0.97 | 0.90–1.05 |
| North Central | 1.03 | 0.97–1.11 | 1.03 | 0.96–1.10 |
| West | 0.93 | 0.86–1.00 | 0.92 | 0.85–0.99 |
| Other/unknown | 1.01 | 0.83–1.22 | 1.01 | 0.83–1.23 |
| Year of first UF-related procedure (reference: 2009) | ||||
| 2010 | 0.94 | 0.87–1.02 | 0.94 | 0.87–1.02 |
| 2011 | 0.97 | 0.90–1.05 | 0.97 | 0.90–1.05 |
| 2012 | 0.99 | 0.91–1.08 | 0.98 | 0.90–1.07 |
| 2013 | 0.95 | 0.87–1.05 | 0.94 | 0.86–1.04 |
| >90 days from initial UF diagnosis to first intervention (reference: ≤90) | 1.08 | 1.02–1.14 | 1.12 | 1.06–1.18 |
| Comorbidities | ||||
| Abdominal pain | 1.10 | 1.03–1.18 | 1.11 | 1.04–1.18 |
| Anemia | 1.29 | 1.22–1.36 | 1.29 | 1.22–1.36 |
| Endometrial polyp/other disorders of the uterus | 0.95 | 0.89–1.02 | 0.95 | 0.89–1.01 |
| Heavy menstrual bleeding | 1.15 | 1.09–1.22 | 1.14 | 1.07–1.21 |
| Infertility | 1.05 | 0.95–1.17 | 1.06 | 0.96–1.18 |
| Obesity | 0.98 | 0.88–1.09 | 0.98 | 0.88–1.09 |
| Other disorders of menstruation or abnormal bleeding | 1.07 | 1.01–1.13 | 1.06 | 1.00–1.11 |
| Ovarian cyst | 0.99 | 0.92–1.07 | 0.99 | 0.92–1.07 |
| Pelvic inflammatory disease | 1.09 | 1.01–1.13 | 1.08 | 1.01–1.16 |
| Pelvic pain | 1.09 | 1.03–1.15 | 1.09 | 1.03–1.16 |
| Urinary problems | 1.10 | 0.97–1.26 | 1.10 | 0.97–1.26 |
| CCI | 1.01 | 0.97–1.04 | 1.01 | 0.97–1.04 |
Source: Truven MarketScan Commercial Claims and Encounters data for 2008–2014.
Estimates were from a Cox proportional hazards model of reintervention after controlling for the initial intervention type and other characteristics assessed before the initial UF intervention. HRs >1 indicate increased hazard of reintervention relative to the reference group.
CI, confidence interval; HR, hazard ratio.