Table 2.
Chromosome aberration test of Xanthigen using CHO-K1 cells.
| Concentrations (μg/mL) |
Chromosomal aberration (%) |
||
|---|---|---|---|
| With S9, 6h Treatmentd |
Without S9, 6 h treatmentd | Without S9, 24 h treatment |
|
| Negative controla | 0.5 | 0.5 | 0.5 |
| Positive controlb, c | 25.5* | 20* | 24* |
| 2500 | 0.5 | 1 | 0.5 |
| 1250 | 1 | 0.5 | 1.5 |
| 625 | 0 | 0.5 | 1.5 |
a
Culture medium containing 10% fetal bovine serum.
b
6 μM mitomicyn C was used without S9.
c
80 μM cyclophosphamide monohydrate was used with S9.
d
Plus 18 h of recovery time.
*
Statistically significant when compared to the negative control group, p <0.05.